Smoking Linked to Increased Dementia Risk Among Depression Patients, Study Finds
Some smokers often say, I crave cigarettes more when Im depressed, but recent research indicates that smoking while in a state of depression significantly increases the risk of developing dementia. A joint research team from Samsung Seoul Hospitals Department of Psychiatry and Soongsil Universitys Department of Information Statistics and Insurance Mathematics utilized data from the National Health Insurance Service. They followed 1,290,530 individuals aged 40 and above who were newly diagnosed with depression between 2009 and 2012, tracking them for an average of 4.26 years until 2020. The study revealed a correlation between smoking and an increased risk of dementia.
During the study period, a total of 58,885 depression patients (4.56%) were confirmed to develop dementia. The research team categorized the subjects based on their smoking status after their depression diagnosis into four groups: non-smoking maintenance group, smoking initiation group, smoking cessation group, and persistent smoking group, and examined the risk of developing dementia.
The results showed that the risk of dementia was 1.34 times higher in the persistent smoking group (141,791 individuals) compared to the non-smoking maintenance group (1,073,517 individuals). The smoking cessation group (48,411 individuals) and smoking initiation group (26,811 individuals) also showed increased risks of 1.26 times and 1.25 times, respectively, when compared under the same conditions.
Notably, even after quitting smoking following a diagnosis of depression, individuals in the smoking cessation group exhibited a dementia risk similar to that of the persistent smoking and smoking initiation groups. A similar trend was observed in the analysis of different types of dementia.
In particular, when considering Alzheimers disease, which accounts for 80% of all dementia cases, the persistent smoking groups risk was found to be 1.32 times higher, while the smoking cessation and initiation groups had risks of 1.26 times each. Vascular dementia, caused by cerebrovascular damage such as hypertension and arteriosclerosis, showed an even more pronounced effect, with the persistent smoking group having a 1.52 times higher risk and the smoking cessation group a 1.47 times higher risk.
The research team stated, Smoking decreases cerebral blood flow, obstructing the oxygen supply to nerve cells. Cigarette smoke...
During the study period, a total of 58,885 depression patients (4.56%) were confirmed to develop dementia. The research team categorized the subjects based on their smoking status after their depression diagnosis into four groups: non-smoking maintenance group, smoking initiation group, smoking cessation group, and persistent smoking group, and examined the risk of developing dementia.
The results showed that the risk of dementia was 1.34 times higher in the persistent smoking group (141,791 individuals) compared to the non-smoking maintenance group (1,073,517 individuals). The smoking cessation group (48,411 individuals) and smoking initiation group (26,811 individuals) also showed increased risks of 1.26 times and 1.25 times, respectively, when compared under the same conditions.
Notably, even after quitting smoking following a diagnosis of depression, individuals in the smoking cessation group exhibited a dementia risk similar to that of the persistent smoking and smoking initiation groups. A similar trend was observed in the analysis of different types of dementia.
In particular, when considering Alzheimers disease, which accounts for 80% of all dementia cases, the persistent smoking groups risk was found to be 1.32 times higher, while the smoking cessation and initiation groups had risks of 1.26 times each. Vascular dementia, caused by cerebrovascular damage such as hypertension and arteriosclerosis, showed an even more pronounced effect, with the persistent smoking group having a 1.52 times higher risk and the smoking cessation group a 1.47 times higher risk.
The research team stated, Smoking decreases cerebral blood flow, obstructing the oxygen supply to nerve cells. Cigarette smoke...
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